RESEARCH ARTICLE
Effects on Sperms’ Quality of Selegiline in Aged Rats
Huba Kalász1, *, Julianna Thuróczy2, Gellért Karvaly3, Lajos Balogh4, István Gyertyán1, Edit Tóth-Molnár5, Ernest Adeghate6, Kornélia Tekes7
Article Information
Identifiers and Pagination:
Year: 2017Volume: 11
First Page: 138
Last Page: 145
Publisher ID: TOMCJ-11-138
DOI: 10.2174/1874104501711010138
Article History:
Received Date: 14/08/2017Revision Received Date: 2/11/2017
Acceptance Date: 13/11/2017
Electronic publication date: 30/11/2017
Collection year: 2017

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4. 0 International Public License (CC-BY 4. 0), a copy of which is available at: https://creativecommons. org/licenses/by/4. 0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background:
Selegiline is used to treat Parkinsonian patients. Other indications of its use have recently been discovered.
Objective:
Scouting special and beneficial side effects of selegiline treatment.
Method:
Two-year old male Wistar rats were daily treated with 0.25 mg/kg of selegiline s.c. (subcutaneous injection). The rats were sacrificed following a four-weeks’ treatment.
Results:
Mass of testes, number of sperms, progressive motility of sperms, and their viability definitely increased.
Conclusion:
Selegiline can successfully be used to stop/counterbalance certain symptoms of aging.