Synthesis of Medicinally Important Quinazolines and Their Derivatives: A Review
Sulochana Sharma1, Kailash Sharma2, Sakshi Pathak3, Mahendra Kumar3, Praveen Kumar Sharma4, *
Identifiers and Pagination:Year: 2020
First Page: 108
Last Page: 121
Publisher Id: TOMCJ-14-108
Article History:Received Date: 24/06/2020
Revision Received Date: 15/09/2020
Acceptance Date: 20/09/2020
Electronic publication date: 27/11/2020
Collection year: 2020
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The study of biodynamic heterosystems has proved to be the most attractive and useful for the development of potential drugs with superior properties and works effectively for the treatment of a variety of diseases, including pandemic ones. Out of the thousand biodynamic heterosystems, the quinazoline heterosystem is one that exhibits wide-ranging biological and pharmacological properties. Synthesis of potential medicinal material is comparatively challenging and needed enough time for clinical trials, testing, permissions for concerned authorities, production and supply. Therefore, researchers usually focused on novel methods incorporated with a high yield of previously approved chemical compounds. This present review article has focused on the synthesis of medicinally important quinazolines and their derivatives, which produce reaction products in less time with high yields, including more attention with eco-friendly green synthesis approaches incorporating multicomponent reactions (MCR), ionic liquids and microwave irradiations.