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Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
The Open Medicinal Chemistry Journal
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27 Mar 2008 •
RESEARCH ARTICLE
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DOI: 10.2174/1874104500802010016
Abstract
This project explores molecular models of Survivin Delta-Ex3, H-Ras, and their binding sites, and generates energy optimized 3D coordinates of docked poses and conformations of the XY2 ligand molecule in the active site of Delta-Ex3. The aim is to propose an effective anti-cancer drug that induces apoptosis and inhibits tumor angiogenesis.