Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein

Z Ezziane*
Department of Information Technology, Higher Colleges of Technology, Al Ain Women’s College, Al Ain, P.O. Box 17258, United Arab Emirates

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 1224
Abstract HTML Views: 637
PDF Downloads: 339
Total Views/Downloads: 2200
Unique Statistics:

Full-Text HTML Views: 491
Abstract HTML Views: 368
PDF Downloads: 251
Total Views/Downloads: 1110

Creative Commons License
Bentham Science Publishers Ltd

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Higher Colleges of Technology, Al Ain Women’s College, Department of IT, P.O. Box 17258, Al Ain, United Arab Emirates; Tel: + 971 3 7095 229; Fax: + 971 3 782 0766; E-mail:


This project explores molecular models of Survivin Delta-Ex3, H-Ras, and their binding sites, and generates energy optimized 3D coordinates of docked poses and conformations of the XY2 ligand molecule in the active site of Delta-Ex3. The aim is to propose an effective anti-cancer drug that induces apoptosis and inhibits tumor angiogenesis.