A New Concept for Smart Drug Delivery: Adhesion Induced Nanovector Implosion§



Nicola M Pugno*
Department of Structural Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Torino, Italy
National Institute of Nuclear Physics, National Laboratories of Frascati, Via E. Fermi 40, 00044, Frascati, Italy


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© Abdullah et al.; Licensee Bentham Open

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Department of Structural Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Torino, Italy; Tel: +39.115644895; Fax: +39.115644899; E-mail: nicola.pugno@polito.it


Abstract

In this paper we show that controlling adhesion in highly flexible nanovectors can help in smartly delivering the drug. The high flexibility of the nanovector is used to smartly deliver the drug only at the target site by the new concept of “adhesion induced nanovector implosion”; a liquid drop analogy is developed for the calculations.