A New Concept for Smart Drug Delivery: Adhesion Induced Nanovector Implosion§
Nicola M Pugno*
Identifiers and Pagination:Year: 2008
First Page: 62
Last Page: 65
Publisher Id: TOMCJ-2-62
Article History:Received Date: 6/3/2008
Revision Received Date: 3/4/2008
Acceptance Date: 4/4/2008
Electronic publication date: 14/5/2008
Collection year: 2008
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
In this paper we show that controlling adhesion in highly flexible nanovectors can help in smartly delivering the drug. The high flexibility of the nanovector is used to smartly deliver the drug only at the target site by the new concept of “adhesion induced nanovector implosion”; a liquid drop analogy is developed for the calculations.