The Open Medicinal Chemistry Journal

Volume 20, 2026

Early View
PUBLISHED ARTICLES


RESEARCH ARTICLEDOI: 10.2174/0118741045455822260514110908 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Covalent Inhibition of Thioredoxin Reductase by Michael Acceptors: Rational Design, Synthesis, and Biological Evaluation of Oxazol-5(4H)-one Derivatives Volume: 20 (2026): e18741045455822 [Electronic Publication Date: June 01, 2026] Veronika Yudina, Alexander Zozulya, Alexander Ognedyuk, Akif Mailov, Alexander Romanishin, Olga Lagunova, Ilia Mallphanov, Ivan Mershiev and Evgeny Chupakhin Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045455658260423122147 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. ROCK2 Inhibition Underlying the Anticancer Effects of Dobutamine: A Novel Proposed Mechanism Volume: 20 (2026): e18741045455658 [Electronic Publication Date: April 27, 2026] Safa Daoud, Alaa Abuawad, Rana Abu-Dahab and Mutasem O. Taha Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045417598260403110551 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Protective Role of Aframomum melegueta against Monosodium Glutamate-induced Prostate Damage in Rats Volume: 20 (2026): e18741045417598 [Electronic Publication Date: April 08, 2026] Asiat Na'Allah, Umar Muhammad Ghali, Şevki Adem, Nadia Mohammed Salama Kurzama, Qendresa Hoti and Fatimah Abubakar Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045448792260324171418 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Targeting WEE1 Kinase with Phytochemicals from Ampelocissus thyrsiflora (Blume) Planch: An Integrated In Silico and In Vitro Study Against Human Breast Cancer Cells Volume: 20 (2026): e18741045448792 [Electronic Publication Date: March 27, 2026] Henny Sri Wahyuni, Sri Yuliasmi, Nazliniwaty, Nilsya Febrika Zebua, Gracelyn Tanaka, Pinastiara Br Napitupulu and Clara Claudia Jap Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045417056260121185145 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. QSAR and Docking Based Screening of Pyrrolidine Derivatives as Matrix Metalloproteinase-2 Inhibitors Volume: 20 (2026): e18741045417056 [Electronic Publication Date: March 26, 2026] Rakesh Kumar Yadav, Phool Chandra and Vaishali M. Patil Abstract View Fulltext HTML PDF Download ePub
MINI-REVIEW ARTICLEDOI: 10.2174/0118741045414768260210115330 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Structural Modifications of Curcumin toward Clinical Applications Volume: 20 (2026): e18741045414768 [Electronic Publication Date: February 25, 2026] Anjani Umarani Wunnava, Kit-Kay Mak, Madhu Katyayani Balijepalli, Shiming Zhang, Jia-Chern Pang and Mallikarjuna Rao Pichika Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045419456251113060848 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Microwave-assisted Green Synthesis and Integrated Bioinformatics Study Reveal Curcumin Analogs Dibenzylidene-cyclohexanones as Novel Potential Anti-Tuberculosis Agents Volume: 20 (2026): e18741045419456 [Electronic Publication Date: February 23, 2026] Ritmaleni, Prajona Marbun, Rosalina Diani Prima Anargya, Ibnu Rahmadiansyah, Muthia Rahayu Iresha, Hendra Gunosewoyo and Muhammad Tahir Akhtar Abstract View Fulltext HTML PDF Download ePub
META ANALYSISDOI: 10.2174/0118741045424657260206053126 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Relationship between Aspirin Resistance and Gene Polymorphism in Chinese Patients with Cerebral Infarction: A Systematic Review and Meta-Analysis Volume: 20 (2026): e18741045424657 [Electronic Publication Date: February 12, 2026] Mohd Hijaz Mohd Sani, Yan Gao, Rhanye Mac Guad and Yu Ning Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045451240260114035356 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Design, Synthesis, and In Vitro Preliminary Cytotoxicity Evaluation of New Anthraquinone-2-Carboxylic Acid Derivatives Volume: 20 (2026): e18741045451240 [Electronic Publication Date: January 29, 2026] Noor Abdulrahman Yaseen and Mohammed Hassan Mohammed Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118741045420705251028094550 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. Therapeutic Potential of Ertugliflozin in Renal Ischemia/Reperfusion Injury by Modulating Nrf2 and Necroptosis Pathways: A Preclinical Study in Rats Volume: 20 (2026): e18741045420705 [Electronic Publication Date: January 08, 2026] Ali F. Jaber and Ali M. Janabi Abstract View Fulltext HTML PDF Download ePub


RESEARCH ARTICLEDOI: 10.2174/0118741045491054260619064621 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. NOTE: Please note that this article is currently in the 'Early view' stage and is not the final 'Version of Record'. While it has been accepted, copy-edited, and formatted, however, it is still undergoing proofreading and corrections by the authors. Therefore, the text may still change before the final publication. Although 'Early view' may not have all bibliographic details available, the DOI and the year of online publication can still be used to cite them. The article title, DOI, publication year, and author(s) should all be included in the citation format. Once the 'Final Version of Record' becomes available the 'Early view' will be replaced by that. Integrated Bioinformatic Modeling of Goniothalamin as a Dual-Target Medicinal Chemistry Candidate Against Antibiotic-Resistant Staphylococcus aureus and Escherichia coli Volume: 20 (2026): e18741045491054 [Electronic Publication Date: July 02, 2026] Nawan Nawan, Septi Handayani and Agnes Immanuela Toemon Abstract View Fulltext HTML PDF
SYSTEMATIC REVIEWDOI: 10.2174/0118741045426493260612105552 All articles published in Open Medicinal Chemistry Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Medicinal Chemistry Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openmedicinalchemistryjournal.com/open-access-policy.php. NOTE: Please note that this article is currently in the 'Early view' stage and is not the final 'Version of Record'. While it has been accepted, copy-edited, and formatted, however, it is still undergoing proofreading and corrections by the authors. Therefore, the text may still change before the final publication. Although 'Early view' may not have all bibliographic details available, the DOI and the year of online publication can still be used to cite them. The article title, DOI, publication year, and author(s) should all be included in the citation format. Once the 'Final Version of Record' becomes available the 'Early view' will be replaced by that. Systematic Review and Meta-Analysis of the Effects of Aged Garlic Extract on Cardiovascular Diseases Volume: 20 (2026): e18741045426493 [Electronic Publication Date: June 19, 2026] Ananya A Ramakrishnan, U A Anushri, Riddhi Daga, Siddhi Daga, A H Manjunatha Reddy, Hadagali Ashoka and Sumathra Manokaran Abstract View Fulltext HTML PDF

RESEARCH ARTICLEDOI: 10.2174/0118741045491054260619064621

Integrated Bioinformatic Modeling of Goniothalamin as a Dual-Target Medicinal Chemistry Candidate Against Antibiotic-Resistant Staphylococcus aureus and Escherichia coli

Volume: 20 (2026): e18741045491054
[Electronic Publication Date: July 02, 2026]

Nawan Nawan, Septi Handayani and Agnes Immanuela Toemon

Abstract View Fulltext HTML PDF

SYSTEMATIC REVIEWDOI: 10.2174/0118741045426493260612105552

Systematic Review and Meta-Analysis of the Effects of Aged Garlic Extract on Cardiovascular Diseases

Volume: 20 (2026): e18741045426493
[Electronic Publication Date: June 19, 2026]

Ananya A Ramakrishnan, U A Anushri, Riddhi Daga, Siddhi Daga, A H Manjunatha Reddy, Hadagali Ashoka and Sumathra Manokaran

Abstract View Fulltext HTML PDF

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Covalent Inhibition of Thioredoxin Reductase by Michael Acceptors: Rational Design, Synthesis, and Biological Evaluation of Oxazol-5(4H)-one Derivatives

ROCK2 Inhibition Underlying the Anticancer Effects of Dobutamine: A Novel Proposed Mechanism

Protective Role of Aframomum melegueta against Monosodium Glutamate-induced Prostate Damage in Rats

Targeting WEE1 Kinase with Phytochemicals from Ampelocissus thyrsiflora (Blume) Planch: An Integrated In Silico and In Vitro Study Against Human Breast Cancer Cells

QSAR and Docking Based Screening of Pyrrolidine Derivatives as Matrix Metalloproteinase-2 Inhibitors

Structural Modifications of Curcumin toward Clinical Applications

Microwave-assisted Green Synthesis and Integrated Bioinformatics Study Reveal Curcumin Analogs Dibenzylidene-cyclohexanones as Novel Potential Anti-Tuberculosis Agents

Relationship between Aspirin Resistance and Gene Polymorphism in Chinese Patients with Cerebral Infarction: A Systematic Review and Meta-Analysis

Design, Synthesis, and In Vitro Preliminary Cytotoxicity Evaluation of New Anthraquinone-2-Carboxylic Acid Derivatives

Therapeutic Potential of Ertugliflozin in Renal Ischemia/Reperfusion Injury by Modulating Nrf2 and Necroptosis Pathways: A Preclinical Study in Rats

Integrated Bioinformatic Modeling of Goniothalamin as a Dual-Target Medicinal Chemistry Candidate Against Antibiotic-Resistant Staphylococcus aureus and Escherichia coli

Systematic Review and Meta-Analysis of the Effects of Aged Garlic Extract on Cardiovascular Diseases

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Volume 20, 2026

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